Williamson, 28, was signed from Watford for an undisclosed fee in the summer of 2009 but had to wait three months before making his debut last season due to the same problem, which has also kept him out for the first half of the current campaign.
Blades manager Micky Adams said: "He's been fit enough to play the last three fixtures and has been fantastic in terms of what he gives, but we've got to be very careful of the workload he's taking on.
"At half-time against Villa he was complaining about having a bit of a tight groin so that's a warning sign, but I think he'll be ok.
"A fit Lee Williamson finally over his problems and without niggles would be a big bonus."
Source: PA
Source: PA