Sheffield United welcome back Chris Morgan and Andy Gray who return from suspension, though the Blades will miss Alan Quinn who received a straight red card in that 1-1 draw to Nottingham Forest.
Alan Wright could return if he recovers from his Stomach infection that kept him out of the Forest game but new signings Emanuele Grabieli or Derek Geary could take his place in Defence.
Meanwhile Simon Francis (knee) and Robert Kozluk (foot) are sidelined.
Predicted Blades XI: Paddy Kenny, Leigh Bromby, Phil Jagielka, Chris Morgan, Jon Harley, Michael Tonge, Paul Thirlwell, Nick Montgomery, Andy Liddell, Paul Shaw, Andy Gray.
Plymouth Argyle welcome back duo David Friio (virus) and Nathan Lowndes (neck) after recovering from their injury's, though Northern Ireland international Tony Capaldi (leg), Hasney Aljofree and Steve Milne will sit this one out.
Predicted Pilgrims XI: Romain Larrieu, David Worrell, Mathias Doumbe, Peter Gilbert, Steve Adams, Graham Coulghlan, David Norris, Ryan Dickson, Lee Makel, Stevie Crawford, Micky Evans.