For the second year running, the popular event will coincide with United's final pre-season fixture. Blackpool are the visitors to Bramall Lane this weekend, which sees the two clubs going through a rebuilding process after each suffering relegation last season.
Last year saw Argentine outfit Estudiantes tackle the Blades at Bramall Lane, with a solitary goal from Matt Lowton giving the hosts the win.
The Open Day begins at 10:00am, and includes behind the scenes tours of Bramall Lane, taking supporters into the newly designed home dressing, which gives fans the chance to see how the much talked about ProZone works.
Tours of the boardroom are also available, whilst the Cherry Street car park will have a hive of activity including a fun fair, stalls and exhibitions, and the chance to step foot on the official team coach which the players travel on to away games.
Players will be on hand to sign any autographs from 10:30am till 12:00pm in the Platinum Suite.
Tours of the dressing room and boardroom finish at 12:30pm due to preparations for the game. The Open Day as a whole concludes at 2:00pm, with the clash against Ian Holloway's Blackpool getting underway at 3:00pm.