Chris Wilder's Blades will be looking to get back to winning ways having not claimed maximum points since they were last on the road at Burton, winning 3-1. Since their victory at the Pirelli Stadium, United have lost at hometo Fulham (4-5) and drew 1-1 with Birmingham City.
Sheffield United defender George Baldock could return to contention for the trip to The Den.
Wing-back Baldock has missed the last four games due to a hamstring strain, but is expected to be included in boss Chris Wilder's squad.
Samir Carruthers and David Brooks are both pushing for starting places after coming off the bench in last week's 1-1 draw with Birmingham.
Midfielder Paul Coutts is out for the season after recently breaking a leg, while striker Ched Evans (ankle) and defender Kieron Freeman (knee) are long-term absentees.
Since following the Blades from League One via the Play-Offs the Lions have made a slow start to the season despite playing some good football. Neil Harris' side lay 19th in the table and just five points ahead of the drop zone.
Jed Wallace is available again for Millwall's Sky Bet Championship game at home to Sheffield United on Saturday.
Wallace has served his three-match suspension and is expected to return, with Fred Onyedinma possibly the one to make way.
Steve Morison and Tom Elliott started up front last weekend but Lee Gregory could be handed a chance to add more of a goal threat.
Shaun Williams is back in training after a knee injury but Saturday will come too soon for the midfielder. Byron Webster remains out, also with a knee problem.