Simonsen, 32 made his United debut in a 1-1 draw at Doncaster Rovers in March 2010 after initially joining on loan from Stoke City, making his move permanent that summer in a free transfer.
The Blades come into this fixture after traveling to Rochdale last Tuesday night, winning at a cantor but had to come from behind before smashing home four goals before the break. Jason Kennedy (3 minutes) headed home at the far post early on to gave Dale a surprise lead but a spectacular volley via Kevin McDonald (5) and a strike from Ched Evans (22) soon put United into the driving seat.
Lee Williamson (25) finished from close range after former Sheffield Wednesday, Barnsley and Leeds United keeper David Lucas parried away Stephen Quinn's shot and Evans (45) grabbed his second of the night before the referee brought the first half to a close. In the second half a long range shot from Michael Doyle (57) evaded the keeper and the score was 5-1; Temitope Obadeyi (68) netted a consolation but despite pushing the Blades they couldn't claw the game back.
Blades boss Danny Wilson now has a selection headache ahead of tomorrow's game; Lescinel Jean-Francois (knee) and Chris Morgan (knee) are both absent through injury. Though he is without Erik Tonne (York City) who is away out on loan. Winger Michael O'Halloran, 21 could make his Sheffield United full debut after arriving on loan from Bolton Wanderers..
Midfielder Nick Montgomery (calf) has returned to the club after receiving an injury whilst on loan at Millwall; he played just nine minutes for the Lions. Midfielder David McAllister has also returned to the Lane, cutting short his loan spell at Shrewsbury Town after being sent off against Aldershot and will now serve a three match suspension, missing fixtures against AFC Bournemouth (1-0), Rochdale (a) and at home against Leyton Orient.
Leyton Orient suffered a huge loss in there battle against relegation with a 3-0 defeat to the hands of Exeter City on Easter Monday, Jake Taylor (4 minutes) opened the scoring before Liam Sercombe (60 & 63) netted a quick-fire brace for the Grecians. The result left the O's just four points above the relegation trap door with Exeter - Blades last day opponents looking doomed with eight points adrift and four games remaining.
They are expected to be without midfielder Jimmy Smith after he suffered a head injury in Good Friday's 3-0 defeat to Nott's County, whilst Leon McSweeney (calf) and former Rotherham United and Barnsley winger Jamal Campbell-Ryce (ankle) are doubtful; defender Scott Cuthbert (hamstring) is sidelined for the season through injury.
Orient boss Russell Slade is likely to field former Sheffield United midfielder Matthew Spring, 32 against his former club. He was signed on loan from Luton Town in July 2008 by then manager Kevin Blackwell - making his debut in a 3-1 League Cup win over Port Vale at Bramall Lane; formerly with Leeds United and Watford he went onto make 10 (+3) appearances for the Blades and scored once before leaving in January 2009 to make a permanent move to Charlton Athletic.